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Latest Publications
  • Borge, L., Bröring, S. (2018). What affects technology transfer in emerging knowledge areas? A multi-stakeholder concept mapping study in the bioeconomy, Journal of Technology Transfer, Link.

  • Sick, N., Preschitschek, N., Leker, J., Bröring, S. (2018). A new framework to assess industry convergence in high technology environments. Technovation. Link

  • Dahabieh, M.S., Bröring, S., Maine E. (2018). Overcoming barriers to innovation in food and agricultural biotechnology. Trends in Food Science & Technology, 79: 204-213. Link

  • Berg, S., Wustmans, M. Bröring, S. (2018). Identifying first signals of emerging dominance in a technoogical innovation system: A novel approach based on patents. Technological Forecasting and Social Change. Link

  • Berg, S., Cloutier, L.M. Bröring, S. (2018). Collective stakeholder representations and perceptions of drivers of novel biomass-based value chains. Journal of Cleaner Production, 200: 231-241. Link

  • Sick, N., Bröring, S., Figgemeier, E. (2018). Start-ups as technology life cycle indicator for the early stage of application: An analysis of the battery value chain. Journal of Cleaner Production, 201: 325-333. Link

  • Kamrath, C., Rajendran, S., Nenguwo, N., Afari-Sefa, V., Bröring, S. (2018). Adoption behavior of market traders: An analysis based on technology acceptance model and theory of planned behaviour. International Food and Agribusiness Management Review, 21(6): 771-790. Link

  • Sick, N., Bröring, S. (2018). Anticipating Industry Convergence in the Context of Industry 4.0. PICMET '18 Conference, "Managing Technological Entrepreneurship: The Engine for Economic Growth", USA.Related information
  • Carraresi, L., Berg, S., Bröring, S. (2018). Emerging value chains within the bio-economy: structural changes in the case of phosphate. Journal of Cleaner Production, 183: 87-101. Link
  • Baum, C. M., Gross, C. (2017): Developing behavior-informed strategies for climate and sustainability policy.Journal of Bioeconomics Special Issue “Transition to Sustainable Economy” 19(1)53-95.
  • Borge, L., Bröring, S. (2017): Exploring effectiveness of technology transfer in interdisciplinary settings- The case of the bioeconomyCreativity and Innovation Management Journal.
  • Bröring, S., Wensing, J. (2017): Functional Ingredients: Market Research. (forthcoming), in: Kirk-Othmer encyclopedia of chemical technology.
  • Butkowski, O., Pakseresht, A., Lagerkvist, C., Bröring, S. (2017): Debunking the Myth of General Consumer Rejection of Green Genetic Engineering: Empirical Evidence from Germany.International Journal of Consumer Studies.
  • Berg, S., Kircher, M., Preschitschek, N., Bröring, S., Schurr, U. (2017): Die Bioökonomie als Kreislauf und Verbundsystem, in: Pietzsch, J Bioökonomie für Einsteiger141-160Springer Spektrum.
  • Bröring, S., Baum, C. M., Butkowski, O., Kircher, M. (2017): Kriterien für den Erfolg der Bioökonomie., in: In J. Pietszch (Ed.), Bioökonomie für Einsteiger161-177Springer Spektrum.
  • Tiso, T., Thies, S., Müller, M., Tsvetanova, L., Carraresi, L., Bröring, S., Jaeger, K.-E., Blank, L. M. (2017): Rhamnolipids: Production, Performance, and Application, in Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals (Edited by Sang Yup Lee)1-37Springer International PublishingLink.
You are here: Home Research Integrated biotransformation and separation of valuable compounds in a novel multiphase loop reactor

Integrated biotransformation and separation of valuable compounds in a novel multiphase loop reactor

Acronym:    InBioSep

Timespan:  11.2017 – 10.2020 (BMBF project)

Resulting from the foreseeable shortage of fossil resources and climate change, a feedstock change from petroleum-based to renewable educts is inevitable. White biotechnology offers a promising possibility by optimizing and tuning microorganisms that metabolize renewable materials combined with efficient processes. One class of high value products that can be produced by microorganisms are sustainable biosurfactants like rhamnolipids. The processes to obtain such products are usually performed in fermenters in large production scale. However, the separation and purification of products from fermentation media lead to new challenges for process engineers concerning product purity, biocompatibility and economic as well as ecologic feasibility. To overcome these limitations in-situ product removal technologies are a good alternative to improve such processes. In this context, the aim of this interdisciplinary project is to develop a new biological fermentation procedure, for the production of rhamnolipids, using a novel multiphase loop-reactor that allows for an in-situ product removal from fermentation media. An analysis of potential market sectors of rhamnolipids will be examined to estimate the diffusion potential of rhamnolipids within different industrial sectors. Based on this, the emerging value chain that accounts for a sustainable and effective production of rhamnolipids will be investigated to understand the most beneficial markets and customers. In addition, the diffusion of the novel multiphase loop-reactor into the market will be investigated. Overall, the InBioSep project interlinks worldwide leading expertise in microbiology and process engineering alongside economics and innovation management. 


Figure 1: Structure of the interdisciplinary collaborative network


Contribution of TIM to the project

In this framework, the TIM Chair contributes to the InBioSep project within the WP5, WP8 and WP9  by tackling the following research goals:

Mapping the knowledge base of the application areas of rhamnolipids (WP5)

  • An analysis of the potential market sectors of rhamnolipids will be performed by drawing upon publications and patent data. Based on these analyses, we will be able to firstly, estimate the diffusion potential of application areas of rhamnolipids into different industrial sectors, and secondly, analyze the knowledge base behind the development and production of rhamnolipids

Analysis of emerging value chains: From feedstock to end users of rhamnolipids (WP8)

  • Based on the scientific literature and patent analysis, selected products containing rhamnolipids will be selected in order to understand the emerging value chain. Expert interviews will be conducted with the members of the industrial steering group as well as value chain members to identify the most beneficial market and customers of products containing rhamnolipids.

Technology transfer: From scientific insights to product applications of rhamnolipids (WP9)

  • This part concerns the question of how to move this technology from basic research to market with a focus on the right organizational approach to understand what is needed in order to transfer the novel approach into commercial applications. Based on expert interviews with the members of the industrial steering group and case studies, we will be able to identify development and commercialization strategies for this particular process innovation.


Link to project: will be available

Laura Borge
Institute for Food and Resource Economics
Chair for Technology and Innovation Management in Agribusiness
Phone: +49-(0)228-73-35 3329


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