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Publikationen und Poster

 

Publikationen

  1. Chatterjee S; Lee LY; Kawahara R; Abrahams JL; Adamczyk B; Anugraham M; Ashwood C; Sumer-Bayraktar Z; Briggs MT; Chik JHL; Everest-Dass A; Förster S; Hinneburg H; Leite KRM; Loke I; Möginger U; Moh ESX; Nakano M; Recuero S; Sethi MK; Srougi M; Stavenhagen K; Venkatakrishnan V; Wongtrakul-Kish K; Diestel S; Hoffmann P; Karlsson NG; Kolarich D; Molloy MP; Muders MH; Oehler MK; Packer NH; Palmisano G; Thaysen-Andersen M. (2019). Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers. Proteomics. 19(21-22), e1900010.
  2. Becker Y; Förster S; Gielen GH; Loke I; Thaysen-Andersen M; Laurini C; Wehrand K; Pietsch T; Diestel S. (2019). Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme. Oncotarget. 10, 4449-4465.
  3. Mohan V; Wyatt EV; Gotthard I; Phend KD; Diestel S; Duncan BW; Weinberg RJ; Tripathy A; Maness PF. (2018). Neurocan Inhibits Semaphorin 3F-induced Dendritic Spine Remodeling through NrCAM in Cortical Neurons. Front. Cell. Neurosci., 12:346. doi: 10.3389/fncel.2018.00346
  4. Homrich M; Es-Saddiki F; Gotthard I; Laurini C; Stein E; Wobst H; Zielinski A; Diestel S (2018). NCAM140 is translocated into the nucleus by an importin-β1-dependent mechanism. Exp. Cell Res. 371, 372-378.
  5. Goschzik T; Cremer H; Gnanapragassam V S; Horstkotte R; Bork K; Schmitz B; Diestel S (2017). Mutation of a putative MAP kinase consensus site regulates NCAM endocytosis and NCAM-dependent neurite outgrowth - Neuroscience Research 120 (2017) 28-35
  6. Homrich M; Gotthard I; Wobst H; Diestel S (2016). Cell adhesion molecules and ubiquitination-functions and significance. Biology 2016, 5, 1; doi:10.3390/biology5010001
  7. Wobst H; Schmitz B; Schachner M;  Diestel S*; Leshchyns'ka, I; Sytnyk V* (2015). Kinesin-1 promotes post_Golgi trafficking of NCAM140 and NCAM180 to the cell surface. – Journal of Cell Science 128, 2816-2829
  8. Dahmen A; Fergen M T; Laurini C; Schmitz B; Loke I; Thaysen-Andersen M; Diestel S (2015). Paucimannosidic glycoepitopes are functionally involved in cell proliferation in the subventricular zone.  Glycobiology, 25, 869-880
  9. Thaysen-Andersen M; Venkatakrishnan V; Loke I; Laurini C; Diestel S; Parker B L; Packer N H (2015). Human Neutrophils Secrete Bioactive Paucimannosidic Proteins from Azurophilic Granules into Pathogen-Infected Sputum - Journal of Biolocal Chemistry, 2015 Apr 3; 290(14):8789-802.
  10. Förster S; Welleford A S; Triplett J C; Sultana R; Schmitz B; Butterfield D A (2014). Increased O-GlcNAc levels correlate with decreased O-GlcNAcase levels in Alzheimer disease brain. BBA Mol Dis 1842):1333-1339.
  11. Swomley A M; Förster S; Keeney J T; Triplett JC; Zhang Z; Sultana R; Butterfield D A (2014). Abeta, oxidative stress in Alzheimer disease: Evidence based on proteomics studies. Biochim Biophys Acta, 2014 Aug; 1842(8): 1248-57.
  12. Homrich M; Wobst H; Laurini C; Sabrowski J; Schmitz B; Diestel S (2014). Cytoplasmic domain of NCAM140 interacts with ubiquitin-fold modifier-conjugating enzyme-1 (Ufc1). Exp. Cell Res. 324: 192-199.
  13. Fiorini A; Sultana R; Förster S; Perluigi M; Cenini G; Cini C; Cai J; Klein J B; Farr S A; Niehoff M L; Morley J E; Kumar V B; Butterfield DA (2013). Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: A proteomics study. Free Radic Biol Med., 65:1-14.
  14. Keeney J T; Förster S; Sultana R; Brewer L D; Latimer C S; Cai J B; Klein J B; Porter N M; Butterfield D A (2013). Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomic changes in levels of key proteins in brain: implications for low vitamin D-dependent age-related cognitive decline. Free Radic Biol Mol., 65: 324-334.
  15. Keeney J T; Swomley A M; Förster S; Harris J L; Sultana R; Butterfield D A (2013). Apolipoprotein A-I: insights from redox proteomics for its role in neurodegeneration. Proteomics Clin Appl., 7: 109-122.
  16. Wobst H; Förster S; Laurini C; Sekulla A; Dreiseidler M; Höhfeld J; Schmitz B; Diestel S (2012). UCHL1 regulates ubiquitination and recycling of the neural cell adhesion molecule NCAM. FEBS J. 279:4398-409.
  17. Zipser B; Bello-DeOcampo D; Diestel S; Tai M H; Schmitz B (2012). Mannitou monoclonal antibody uniquely recognizes paucimannose, a marker for human cancer, stemness and inflammation. J. Carbohydr. Chem. 31: 504-518.
  18. Marx M; Diestel S; Bozon M; Keglowich L; Drouot N; BouchéE; Frebourg T; Minz M; Saugier-Veber P; Castellani V; Schäfer M K E (2012). Pathomechanistic characterization of two exonic L1CAM variants located in trans in an obligate carrier of X-linked hydrocephalus. Neurogenetics, 13: 49-59.
  19. Schäfer M K E; Schmitz B; Diestel S (2010). L1 ubiquitination facilitates its lysosomal degradation. FEBS Lett., 584:4475-4480.
  20. Renker B; Diestel S; Ruonala M; Bertram J (2010). MATra – ein trojanisches Pferd für eine zellschonende Transfektion. BIOspektrum, 04/10:441-442.
  21. Boutin C; Schmitz B; Cremer H; Diestel S (2009). NCAM expression induces neurogenesis in vivo. Eur. J. Neurosci., 30:1209-1218.
  22. Boutin C; Diestel S; Desoeuvre A; Tiveron M C; Cremer H (2008). Efficient in vivo electroporation of the postnatal rodent forebrain. PloS One, 3:e1883.
  23. Diestel S; Schaefer D; Cremer H; Schmitz B (2007). NCAM is ubiquitylated, endocytosed and recycled in neurons. J. Cell Sci., 120:4035-4049.
  24. Schultheis M; Diestel S; Schmitz B (2007). The role of cytoplasmic serine residues of L1 in neurite outgrowth, endocytosis and cell migration. Cell. Mol. Neurobiol., 27:11-31.
  25. Hinkle C L; Diestel S; Lieberman J; Maness P F (2006). Metalloprotease-induced ectodomain shedding of neural cell adhesion molecule (NCAM). J. Neurobiol., 66:1378-1395.
  26. Diestel S; Hinkle C L; Schmitz B; Maness P F (2005). NCAM140 stimulates integrin-dependent cell migration by ectodomain shedding. J. Neurochem., 95:1777-1784.
  27. Diestel S; Laurini C; Traub O; Schmitz B (2004). Tyrosine 734 of NCAM180 interferes with the FGF receptor-dependent signaling implicated in neurite growth. Biochem. Biophys. Res. Com., 322:186-196.
  28. Diestel S; Eckert R; Hülser D; Traub O (2004). Exchange of serine residues 263 and 266 reduces the function of mouse gap junction protein Connexin31 and exhibits a dominant-negative effect on the wild type protein in HeLa cells. Exp. Cell Res., 294:446-457.
  29. Diestel S; Richard G; Döring B; Traub O (2002). Expression of a connexin31 mutation causing Erythrokeratodermia variabilis is lethal for HeLa cells. Biochem. Biophys. Res. Commun., 296: 721-728.
  30. Traub O; Diestel S; Nam S W (2002). Kaloderma oder Keratoderma? Bioforum, Sonderausgabe “Zellbiologie”:26-28.
  31. Wenzel U; Kuntz S; Diestel S; Daniel H (2002). PEPT1-mediated cefixime uptake into human intestinal epithelial cells is increased by Ca2+-channel blockers. Antimicrob. Agents and Chemother., 46:1375-1380.
  32. Wenzel U; Diestel S; Daniel H (1998). Welche Rolle spielt der intestinale Peptidtransporter für die orale Verfügbarkeit anionischer und zwitterionischer beta-Lactamantibiotika. Zeitschrift für Gastroenterologie, Suppl. 1:24-28.

 

Posterpräsentationen

  1. Becker Y; Förster S; Gielen GH; Loke I; Thaysen-Andersen M; Laurini C; Schäfer M; Pietsch T; Diestel S. (2019) Paucimannosidic glycoepitopes in glioblastoma multiforme. Brain Tumor Meeting, 23.05.2019-24.05.2019, Berlin, Germany
  2. Becker Y; Förster S.; Loke I.; Thaysen-Andersen M.; Laurini C.; Benndorf J.; Diestel S. (2017). Paucimannose is expressed in glioblastoma and regulates different tumorigenic processes. 28th Joint Glycobiology Meeting, 17.09.2017-19.09.2017, Aachen, Germany
  3. Förster S; Wehrand K; Laurini C; v Quistorp H; Diestel S (2016). Role of Paucimannosidic Glycoepitopes in Tumorigenic Processes. 16.10.16 - 18.10.16, 27th Yoint Glycobiology Meeting, Nijmegen, NL
  4. Jockschat C; Laurini C; Diestel S; Günther K; (2016). Die Wirkung von Nonylphenolen auf die Entwicklung des Nervensystems. 45. Deutscher Lebensmittelchemikertag, 12.09.16 - 14.09.16, Freising-Weihenstephan, Germany
  5. Loke I; Venkatakrishnan V; Laurini C; Diestel S; Parker BL; Packer NH; Thaysen-Andersen ; (2015). Structure, function and biosynthesis of a new class of human N-glycosylated neutrophilics proteins in pathogen-infected sputum. FEBS Journal, Vol 282, p47, Supp 1, SI.
  6. Dahmen A; Fergen MT; Laurini C; Zipser B; Schmitz B; Diestel S (2014). Paucimannose influences cell proliferation of neural stem cells and different cancer cell lines. 25th Joint Glycobiology Meeting, 14.9.2014-16.9.2014, Ghent, Belgium.
  7. Wobst H; Schmitz B; Leshchyns’ka I; Diestel S*; Sytnyk V* (2014). Kinesin-1 is involved in the transport of the neural cell adhesion molecules (NCAM) to the cell surface. *= equal contribution, 3rd International Symposium on Protein Trafficking in Health and Disease 10.09.2014-12.09.2014, Hamburg, Germany.
  8. Förster S; Sultana R; Butterfield DA; Schmitz B (2014). O-GlcNAc – a posttranslational modification implicated in AD? International Meeting of the GBM study group „Molecular Neurobiology“ 11.09.2014-13.09.2014, Bochumn, Germany
  9. Jockschat C; Frank J; Diestel S (2014). Curcumin fördert die Differenzierung von Nervenzellen. Posterpräsentation bei dem wissenschaftlichen Kongress der Deutschen Gesellschaft für Ernährung (DGE), 12.03.2014, Paderborn.
  10. Wobst H; Faraidun H; Sekulla A; Dreiseidler M; Höhfeld J; Schmitz B; Diestel S (2012). UCHL1 regulates ubiquitination and recycling of the neural cell adhesion molecule NCAM. 63. Mosbacher Kolloquium 29.3.2012-31.3.2012.
  11. Förster S; Gehrig BJ; Balzen S; Diestel S; Schmitz B (2012). Analytical tools for the identification of O-GlcNAc modified proteins: from Western blots to mass spectrometric sequencing. 63. Mosbacher Kolloquium 29.3.2012-31.3.2012.
  12. Förster S; Strempel N; Gehrig B J; Schmitz B (2011). Development of an in vitro OGT assay using recombinant OGT. 22nd Joint Glycobiology Meeting 28.-29.11.2011, Lille.
  13. Diestel S; Fergen M T; Gehrig B J; Schmitz B; Zipser B (2011). Trimannosyl structure on stem cells and carcinomas/inflamed tissue recognized by Mannitou antibody. International Fall Meeting of the German Society for Biochemistry and Molecular Biology, 25.09.2011-28.09.2011.
  14. Wobst H; Sekulla A; Laurini C; Schmitz B; Diestel S (2011). Protein macroarray: a new approach to identify NCAM binding partners. 9th Göttingen Meeting 2011 of the German Neuroscience Society, Abstr. T27-4C.
  15. Schaefer M K E; Schmitz B; Diestel S (2011). L1CAM ubiquitination facilitates its lysosomal degradation. 9th Göttingen Meeting 2011 of the German Neuroscience Society, Abstr. T2-9C.
  16. Goschzik T; Salomon A; Schmitz B; Diestel S (2010). Deletion of the C-terminal ENESKA domain of NCAM leads to increased cell migration on laminin. 7th FENS Forum of European Neuroscience, Amsterdam, Abstr. 073.11.
  17. BoutinC; Schmitz B; Cremer H; Diestel S (2009). In vivo electroporation of NCAM influences proliferation of neural stem cells PSA-independently. 8th Göttingen Meeting 2009 of the German Neuroscience Society, Abstr. T7-9C.
  18. BoutinC; Schmitz B; Cremer H; Diestel S (2008). NCAM influences proliferation of neural stem cells in the postnatal mouse brain. Joint Glycobiology Meeting, Wageningen.
  19. Hinkle C L; Diestel S; Lieberman J; Maness P F (2005). Ectodomain shedding of neural cell adhesion molecule (NCAM): mechanisms and neuronal connectivity. 35th Annual Meeting in Washington D.C., Society for Neuroscience, Abstr. 600.9.
  20. Goschzik T; Quade R; Kominek V; Laurini C; Maness P F; Schmitz B; Diestel S. (2005). The role of the phosphorylation of threonine 803 of human N-CAM in endocytosis and neurite outgrowth. 6th Meeting of the German Neuroscience Society, 30th Göttingen Neurobiology Conference, Göttingen, Abstr. 362 A.
  21. Diestel S; Laurini C; Buschwald R; Streit A; Brüstle O; Schmitz, B (2005). Expression of Lewis X during neural differentiation of murine embryonic stem cells and P19 EC cells. CFG-Meeting, Bethesda/USA.
  22. Diestel S; Laurini C; Traub O; Schmitz B (2004). NCAM180 tyrosine phosphorylation plays a key role in the FGF receptor dependent signaling pathway implicated in neurite outgrowth. 34th Annual Meeting in St. Diego, Society for Neuroscience, Abstr. 723.11.
  23. Diestel S; Müller C; Fergen M T; Laurini C; Traub O; Schmitz B (2003). The role of NCAM phosphorylation in NCAM mediated signal transduction pathways. Proceedings of the. 29th Göttingen Neurobiology Conference and the 5th Meeting of the German Neuroscience Society, Abstr. 869.
  24. Diestel S; Buschwald R; Streit A; Brüstle O; Schmitz B (2002). Expression of the L5 carbohydrate epitope during differentiation of murine embryonic stem cells. Glycobiology 12, Abstr. 113.
  25. Kellersmann J; Diestel S; Schmitz B (2002). The O-Glc-NAc modification of proteins interferes with signaling by PKA and CDK5 dependent phosphorylation in neurons. 3th Forum of European Neuroscience, Paris, 13.07.02 – 17.07.02. Gemeinsame Herbsttagung GBM und DGPT in Halle (Saale), 07.09.02 – 10.09.02, DOI: 10.1240/sav_gbm_2002_h_000122, 1.20.
  26. Schultheis M; Diestel S; Schmitz B (2002). The role of serine phosphorylation of the cell adhesion molecule L1 in basal neurite outgrowth. Gemeinsame Herbsttagung GBM und DGPT in Halle (Saale), 07.09.02 – 10.09.02, DOI: 10.1240/sav_gbm_2002_h_000121, 1.22.

 

 

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